General information, not an individual diagnosis. Ask a healthcare professional if you are unsure about your situation.
During colchicine treatment, diarrhoea with or without nausea or vomiting can be an early sign of serious overdose. The COLCHICINE OPOCALCIUM and COLCHIMAX leaflets require prompt medical contact. This warning must not wait for a prevention check.
If more than the prescribed amount has been taken, both leaflets require immediate contact with a doctor, poison centre or urgent care service. This applies even when the person’s condition appears unchanged: waiting for symptoms is insufficient.
The cited product information describes a narrow therapeutic margin: the gap between useful and toxic exposure is limited. This explains attention to digestive warning signs. Persistent pain does not authorise increasing the medicine yourself.
Both leaflets require medical consultation for liver or kidney disease. Tell the prescriber about known kidney or liver conditions. The leaflets also advise seeking medical or pharmaceutical advice when in doubt.
Some antibiotics must not be combined with colchicine. The leaflets name pristinamycin and macrolides, with the exception of spiramycin. Show every new prescription to a professional to check the exact combination, without replacing either treatment yourself.
For long-term treatment, both leaflets provide for regular blood count monitoring. Bring the product name and clarify the planned follow-up. If diarrhoea occurs, the doctor may decide to reduce or suspend treatment; no personal dose calculation is provided here.
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